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BANA assay를 이용한 치주질환 환자의 세균검출에 관한 연구
A study on detection of periodontopathic bacteria in periodontal disease by means of the BANA assay

구강생물학연구 1992년 16권 2호 p.519 ~ 528

염창엽, 김병옥, 이장희, 한경윤, 김재덕,

소속 상세정보

염창엽 ( Yum Chang-Yup ) - 조선대학교 치과대학 치주과학교실
김병옥 ( Kim Byung-Ok ) - 조선대학교 치과대학 치주과학교실
이장희 ( Lee Zang-Hee ) - 조선대학교 치과대학 치주과학교실
한경윤 ( Han Kyung-Yoon ) - 조선대학교 치과대학 치주과학교실
김재덕 ( Kim Jae-Duk ) - 조선대학교 치과대학 치주과학교실

KMID : 0353319920160020519

Abstract

The present study evaluated the potential of a easy rapid test system for the detection of specific bacterial enzymatic activities in some periodontally defined populations. Most forms of periodontal disease are associated with the presence or
overgrowth of anaerobic species that would include Treponema denticola, Porphyromonas (Bacteroides) gingivalis and Bacteroides forsythus among the cultivable plaque species in that they hydrolyze the synthetic trypsin substrate,
benzoyl-DL-arginine-naphthylamide (BANA). In turn, BANA hydrolysis by the plaque can be associated with periodontal morbidity and with the presence of these BANA-positive organisms in the plaque. In this study, the results of BANA test were
compared
with plaque index and gingival index by means of canonical corelation analysis.
@ES The results were as follows:
@EN 1. As the BANA scores were very significantly related to plaque index (R=0.967, p<0.05), BANA hydrolytic bacteria were isolated in higher proportions from subgingival plaque according to increase in plaque index.
2. As the BANA scores were very significantly related to gingival index(R-0.943, P<0.05), BNAN hydrolytic bacteria were isolated in higher proportions from subgingival plaque according to increase in gingival index.